Giving vehicles for philanthropists who want to engage and fund in science and medicine are expanding, and less philanthropists and corporations are following the traditional ‘foundation’ model of grantmaking. In its place we see an increase in the venture philanthropy model directed by individuals who employ organizations with grantmaking and science/medicine backgrounds to strategically run grant programs for them for maximum impact. The Milken Institute Center for Strategic Philanthropy (CSP) advises philanthropists and foundations seeking to develop and implement transformative giving strategies. In the past ten years alone, CSP has advised over $2 billion in funding on behalf of philanthropists and that number continues to grow. This session will cover two important areas. First, CSP staff/program directors will give an overview of CSP, their strategic goals with philanthropists, and the breadth of depth of their work. Second, the panel will explore this model of venture philanthropy, how organizations like CSP and academia can successfully work together on impactful communication to philanthropists, and how CFR professionals play a role in this model.